Sean O'Brien Selected Research

CX 3543

10/2009

Anticancer activity of CX-3543: a direct inhibitor of rRNA biogenesis.

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Sean O'Brien Research Topics

Disease

4	Aortic Valve Stenosis (Aortic Stenosis) 11/2019 - 11/2013
3	Neoplasms (Cancer) 01/2016 - 10/2009
3	Hemorrhage 04/2013 - 01/2012
2	Endocarditis 04/2013 - 01/2011
2	ST Elevation Myocardial Infarction 07/2011 - 09/2010
2	Myocardial Infarction 11/2007 - 05/2006
1	Coronary Artery Disease (Coronary Atherosclerosis) 01/2022
1	Cryptorchidism (Undescended Testes) 10/2021
1	Chronic Kidney Failure (Chronic Renal Failure) 11/2019
1	Neuroinflammatory Diseases 12/2018
1	Status Epilepticus (Complex Partial Status Epilepticus) 12/2018
1	Multiple Myeloma 01/2017
1	Left Ventricular Dysfunction 01/2016
1	Lymphoma (Lymphomas) 01/2016
1	Heart Failure 01/2016
1	Stroke (Strokes) 04/2013
1	Hypertrophy 01/2013
1	Osteoarthritis 01/2013
1	Osteolysis 03/2012
1	Thromboembolism 01/2012
1	Inflammation (Inflammations) 11/2011
1	Rheumatoid Arthritis 11/2011
1	Inflammatory Breast Neoplasms 11/2011
1	Neoplasm Metastasis (Metastasis) 11/2011
1	Renal Insufficiency (Renal Failure) 01/2011
1	Cardiac Arrhythmias (Arrythmia) 01/2011
1	Hypertension (High Blood Pressure) 01/2011
1	Lung Diseases (Lung Disease) 01/2011
1	Cardiogenic Shock 01/2011
1	Lung Neoplasms (Lung Cancer) 08/2010
1	Constipation 11/2009
1	Carcinoid Tumor (Carcinoid) 10/2009
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 10/2009
1	Carcinogenesis 10/2009
1	Acquired Immunodeficiency Syndrome (AIDS) 09/2007
1	Infections 09/2007

Drug/Important Bio-Agent (IBA)

2	Ribosomal DNA (rDNA)IBA 01/2016 - 10/2009
2	Proteins (Proteins, Gene)FDA Link 01/2016 - 10/2009
2	Warfarin (Coumadin)FDA LinkGeneric 09/2012 - 01/2012
1	A 7 (A-7)IBA 10/2021
1	BenzodiazepinesIBA 12/2018
1	cyclo(cysteinyl- tyrosyl- norleucyl- glycyl- tryptophyl- cysteinyl)- aspartyl- phenylalaninamide (Es1)IBA 12/2018
1	Nerve AgentsIBA 12/2018
1	Midazolam (Versed)FDA LinkGeneric 12/2018
1	SomanIBA 12/2018
1	Carboxylesterase (Hydrolase S)IBA 12/2018
1	RNA Polymerase I (Polymerase I, RNA)IBA 01/2017
1	CX 5461IBA 01/2017
1	Eukaryotic Initiation Factor-4EIBA 01/2016
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2016
1	Everolimus FDA Link 01/2016
1	Anabolic AgentsIBA 01/2013
1	CollagenIBA 01/2013
1	ErbB Receptors (EGF Receptor)IBA 01/2013
1	Aggrecans (Aggrecan)IBA 01/2013
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 09/2012
1	Polyethylene (Polythene)IBA 03/2012
1	MetalsIBA 03/2012
1	CytokinesIBA 11/2011
1	Interleukin-6 (Interleukin 6)IBA 11/2011
1	silmitasertibIBA 11/2011
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 11/2011
1	Casein Kinase II (Casein Kinase 2)IBA 11/2011
1	Insulin (Novolin)FDA Link 01/2011
1	CreatinineIBA 01/2011
1	CX 3543IBA 10/2009
1	Phosphotransferases (Kinase)IBA 10/2009
1	NucleolinIBA 10/2009
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 09/2007
1	dipropylenetriamine-NONOateIBA 09/2007

Therapy/Procedure

4	Transcatheter Aortic Valve Replacement 11/2019 - 11/2013
3	Therapeutics 11/2019 - 01/2016
2	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2022 - 05/2006
2	Percutaneous Coronary Intervention 07/2011 - 09/2010
1	Bioprosthesis 04/2013
1	Renal Dialysis (Hemodialysis) 01/2011
1	Pneumonectomy (Lung Volume Reduction) 08/2010
1	Colectomy 11/2009
1	Length of Stay 11/2007